Prevalence of Subclinical Vitamin D Deficiency in Different European Countries

@article{Scharla1998PrevalenceOS,
  title={Prevalence of Subclinical Vitamin D Deficiency in Different European Countries},
  author={Stephan H. Scharla},
  journal={Osteoporosis International},
  year={1998},
  volume={8},
  pages={S7-S12}
}
  • S. Scharla
  • Published 1998
  • Medicine
  • Osteoporosis International
Long-lasting and severe vitamin D deficiency leads to osteomalacia, a metabolic bone disease characterized by typical biochemical abnormalities (low serum concentrations of calcium and phosphate, increased activity of alkaline phosphatase). Bone histology shows decreased mineralization of bone matrix, increased osteoid volume and decreased bone formation. Vitamin D deficiency can be confirmed by measuring the serum concentration of 25-hydroxyvitamin D (25(OH)D), which is the major circulating… Expand
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