Prevalence of Streptococcal Pharyngitis and Streptococcal Carriage in Children: A Meta-analysis

@article{Shaikh2010PrevalenceOS,
  title={Prevalence of Streptococcal Pharyngitis and Streptococcal Carriage in Children: A Meta-analysis},
  author={Nader Shaikh and E Leonard and Judith M. Martin},
  journal={Pediatrics},
  year={2010},
  volume={126},
  pages={e557 - e564}
}
OBJECTIVES: Prevalence estimates can help clinicians make informed decisions regarding diagnostic testing of children who present with symptoms of pharyngitis. We conducted a meta-analysis to determine the (1) prevalence of streptococcal infection among children who presented with sore throat and (2) prevalence of streptococcal carriage among asymptomatic children. METHODS: We searched Medline for articles on pediatric streptococcal pharyngitis. We included articles in our review when they… Expand
View on AAP
ncbi.nlm.nih.gov
339 Citations
Highly Influential Citations
6
Background Citations
88
Methods Citations
2
Results Citations
4

339 Citations

Citation Type

Citation Type

Streptococcal pharyngitis in children: a meta-analysis of clinical decision rules and their clinical variables
TLDR
The rule of Joachim et al could be useful for clinicians who do not use rapid diagnostic tests and should allow avoiding antibiotic treatment for the 35% of children identified by the rule as not having GAS pharyngitis. Expand
Group A Streptococcus pharyngitis and pharyngeal carriage: A meta-analysis
TLDR
In active sore throat management programmes, if the prevalence of GAS detection approaches the asymptomatic carriage rate (around 6–11%), there may be little benefit from antibiotic treatment as the majority of culture-positive patients are likely carriers. Expand
Diagnosis of streptococcal pharyngotonsillitis in children and adolescents: clinical picture limitations☆
TLDR
It is necessary to enhance laboratory test availability, especially of LPATs that allow an acurate and fast diagnosis of streptococcal pharyngotonsilitis, because its performance as a diagnostic test is low. Expand
Prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Uganda
TLDR
There is a high prevalence of GAS pharyngeal carriage among children aged 5–15 years attending primary schools in Wakiso District, Uganda, with peri-urban schools more likely to have children with GAS compared to rural schools. Expand
Beta‐Hemolytic Nongroup A Streptococcal Pharyngitis in Children
TLDR
Infections associated with NGAS are milder than with GAS, and complications are rare, and Laboratory reporting of NGAS results in high antibiotic use, despite current recommendations against treatment. Expand
Presence of microorganisms in children with pharyngotonsillitis and healthy controls: a prospective study in primary healthcare
TLDR
Bacteria were more common than viruses in both study groups, and the high rate of pathogens in asymptomatic children interferes with diagnoses based on aetiology. Expand
Clinical Features of Group A Streptococcus in Children With Pharyngitis: Carriers versus Acute Infection
TLDR
Children with symptomatic pharyngitis and GAS on throat culture identified as carriers were more likely to present with URI and atypical symptoms than children who were acutely infected. Expand
Viral Features and Testing for Streptococcal Pharyngitis
This study shows that the majority of patients tested for GAS pharyngitis have features more consistent with a viral illness than with a bacterial infection. BACKGROUND AND OBJECTIVES: The Infectious… Expand
Group A Streptococcal Pharyngitis Testing Appropriateness in Pediatric Acute Care Settings.
TLDR
Quality improvement initiatives are needed to decrease the rate of inappropriate streptococcal rapid antigen detection tests (RADT) in pediatric UCC and ED settings. Expand
Adherence to guidelines for testing and treatment of children with pharyngitis: a retrospective study
TLDR
The majority of GAS tests in children with pharyngitis are indicated, although providers do not regularly document all elements of a validated pharygitis scoring tool, and over one quarter of children prescribed antibiotics for pharyNGitis did not require antibiotics according to guidelines. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 47 REFERENCES
Streptococcal pharyngitis in Italian children: epidemiology and treatment with miocamycin.
A prospective multicentre study of Italian children with acute pharyngotonsillitis was carried out to determine the incidence of beta-haemolytic streptococcal infection and its epidemiological… Expand
Evaluation of the WHO clinical decision rule for streptococcal pharyngitis
TLDR
In these populations, the current WHO CDR has high specificity, but low sensitivity; it did not detect up to 96.0% of children who have laboratory confirmed GABHS pharyngitis; a CDR with higher sensitivity should be developed for use in regions where rheumatic fever and rheumat heart disease are still major health problems. Expand
Prevalence of non-group-A beta-hemolytic streptococci in childhood pharyngitis.
TLDR
This study demonstrates an association between NGAS and sporadic pharyngitis in school children but does not establish causality and seasonal variation in the recovery of NGAS from symptomatic children was suggested by higher relative and absolute recovery rates of NG AS during warm weather. Expand
The burden of group A streptococcal pharyngitis in Melbourne families.
TLDR
The present data suggest that GAS pharyngitis remains very common in childhood, and that it has further implications in terms of secondary cases and costs. Expand
Performance of a predictive model for streptococcal pharyngitis in children.
TLDR
A pediatric predictive model for GABHS pharyngitis performed better than physicians' subjective estimates for a positive throat culture and was comparable with a rapid antigen detection test, and performed consistently well in different populations and across seasons. Expand
Incidence of streptococcal carriers in private pediatric practice.
TLDR
A small percentage of children seen in private pediatric practices who are well or who have apparent viral upper respiratory tract infections with sore throat are GABHS carriers. Expand
Viral and bacterial organisms associated with acute pharyngitis in a school-aged population.
To investigate the causes and clinical characteristics of acute pharyngitis among school-aged children (4 to 18 years), we obtained throat cultures for respiratory viruses, Mycoplasma pneumoniae,… Expand
Selective utilization of clinical diagnosis in treatment of pharyngitis.
: Exudate, adenopathy, and fever were used to predict clinically whether pharyngitis was streptococcal, nonstreptococcal, or questionable in 466 adults and 234 children. Clinical accuracy was:… Expand
Selective utilization of clinical diagnosis in treatment of pharyngitis.
  • R. Forsyth
  • Medicine
  • The Journal of family practice
  • 1975
TLDR
It is recommended that throat culture be obtained for all questionable patients and clinically nonstreptococcal children, and Penicillin should be administered orally in the majority of adults. Expand
Empirical validation of guidelines for the management of pharyngitis in children and adults.
TLDR
Assessing the impact of guideline recommendations and alternative approaches on identification and treatment of GAS pharyngitis in children and adults found strategies incorporating throat culture or throat culture confirmation of negative rapid antigen test results are highly sensitive and specific. Expand
...
1
2
3
4
5
...