Prevalence of Helicobacter pylori infection in peptic ulcer perforations.

  title={Prevalence of Helicobacter pylori infection in peptic ulcer perforations.},
  author={J{\"u}rg Metzger and S. Styger and Cornel Christian Sieber and Markus O von Fl{\"u}e and Peter Vogelbach and Felix Harder},
  journal={Swiss medical weekly},
  volume={131 7-8},
BACKGROUND Most patients with chronic peptic ulcer disease have Helicobacter pylori (H. pylori) infection. In the past, immediate acid-reduction surgery has been strongly advocated for perforated peptic ulcers because of the high incidence of ulcer relapse after simple closure. Simple oversewing procedures either by an open or laparoscopic approach together with H. pylori eradication appear to supersede definitive ulcer surgery. METHODS In 47 consecutive patients (mean age = 64 years, range… CONTINUE READING
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