Prevalence of Gs alpha mutations in Korean patients with pituitary adenomas.

  title={Prevalence of Gs alpha mutations in Korean patients with pituitary adenomas.},
  author={H J Kim and Myung Soon Kim and Young Joo Park and Sang Wan Kim and Do Joon Park and Kyong Soo Park and Sung Yeun Kim and Bo Youn Cho and Hee Keun Lee and Hee Won Jung and Do Hoon Han and Hyeon Sook Lee and Je Geun Chi},
  journal={The Journal of endocrinology},
  volume={168 2},
The reported frequencies of Gs alpha mutations (gsp mutations) in growth hormone (GH)-secreting pituitary adenomas are variable (ranging from 4.4 to 43%), and the presence of these mutations in the other pituitary adenomas is still a matter of controversy. Previous clinical and biochemical analyses of patients with GH-secreting pituitary adenomas and gsp mutations produced conflicting results and did not demonstrate obvious characteristics. Therefore, we investigated the prevalence of gsp… CONTINUE READING
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Analysis of the Gs gene in growth hormone-secreting pituitary adenomas by the polymerase chain reaction-direct sequencing method using paraffin-embedded tissues

  • E Hosoi, Y Yokogoshi, H Horie, T Sano, S Yamada, S Saito
  • Acta Endocrinologica
  • 1993
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