Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Cuba

  title={Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Cuba},
  author={Rolando Comacho Rodriguez and Antonio Alejandro Esperon and Ramon Ropero and Maria Caridad Rubio and Ronald Rodriguez and Rosa Maria Ortiz and Juan J. Lence Anta and Mario de los Rios and Deyanira Carnesolta and Maria C. del Olivera and Somalia Stiu Vansam and Robert Royer and Mohammad R. Akbari and Talia R Donenberg and Steven A Narod},
  journal={Familial Cancer},
The contribution of BRCA1 and BRCA2 to breast cancer incidence in Cuba has not yet been explored. In order to estimate the proportion of breast cancers due to BRCA1 and BRCA2 mutations in Cuba, and to identify possible Cuban founder mutations, we conducted a study of unselected breast cancer patients from Havana, Cuba. We enrolled 336 women with breast cancer from a large public hospital in the city. A family history of cancer was obtained from each patient and a blood sample was processed for… CONTINUE READING

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A fluorescent multiplexed-DGGE (FMD) screening test for the BRCA1 gene

  • G Kuperstein, E Jack, H Risch, J McLaughlin, SA Narod
  • Genet Test
  • 2006
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