Prevalence of A2143G mutation of H. pylori-23S rRNA in Chinese subjects with and without clarithromycin use history

@article{Liu2007PrevalenceOA,
  title={Prevalence of A2143G mutation of H. pylori-23S rRNA in Chinese subjects with and without clarithromycin use history},
  author={Zhuoqi Liu and Jing Shen and Lian Zhang and Lin Shen and Qiang Hua Li and Baozhen Zhang and Jing Zhou and Liankun Gu and Guoshuang Feng and Junling Ma and Wei-cheng You and Dajun Deng},
  journal={BMC Microbiology},
  year={2007},
  volume={8},
  pages={81 - 81}
}
A2143G mutation of 23S rRNA gene of H. pylori results in clarithromycin (CLR) resistance. To investigate the prevalence of the CLR resistance-related A2143G mutation of the H. pylori-specific 23S rRNA gene in Chinese subjects with and without CLR use history, 307 subjects received the treatment with amoxicillin and omeprazole (OA) and 310 subjects received a placebo in 1995, and 153 subjects received a triple therapy with OA and CLR (OAC) in 2000. DNA was extracted from fasting gastric juice at… CONTINUE READING

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