Prevalence and topographical distribution of colorectal adenomas. — A study on 1006 autopsies

Abstract

Ultrastructurally we identified seven different cell types in colorectal adenocarcin~ma: undifferentiated cell (UC), intermediate cell (IC), immature goblet cell (IG), im~ture absorptive cell (IA), mature goblet cell (MG), mature absorptive cell (MA) and enterochromaffin cell (EC). These cell types were present in variable amounts in light microscopically well, moderately and poorly differentiated carcinomas. lhere was a good correlation between the light microscopic and the electren microscopic grading, when the light microscopic grading was based on three criteria: cell polarity, nuclear atypia and s t ra t i f i cation. Other light microscopical criteria, such as glandular arrangement, budding,branching, bridging and papillary formations were of less predictive value in view of the degree of ultrastructural cytoplasmatic differentiation.

DOI: 10.1007/BF02580120

Cite this paper

@article{Gabbert2007PrevalenceAT, title={Prevalence and topographical distribution of colorectal adenomas. — A study on 1006 autopsies}, author={H. E. Gabbert and C. -D. Gerharz and Ross I Wagner}, journal={Journal of Cancer Research and Clinical Oncology}, year={2007}, volume={111}, pages={S88-S88} }