Prevalence and spectrum of GATA4 mutations associated with sporadic dilated cardiomyopathy.

@article{Li2014PrevalenceAS,
  title={Prevalence and spectrum of GATA4 mutations associated with sporadic dilated cardiomyopathy.},
  author={Jian Li and Wei-Dong Liu and Zhang-Liang Yang and Fang Yuan and Lei Xu and Ruo-gu Li and Yi-Qing Yang},
  journal={Gene},
  year={2014},
  volume={548 2},
  pages={174-81}
}
Dilated cardiomyopathy (DCM) is the most frequent type of primary myocardial disorder responsible for substantial morbidity and mortality. DCM is the third most common cause of heart failure and the most common reason for heart transplantation. A recent study has implicated GATA4 mutation in the pathogenesis of familial DCM. However, the prevalence and spectrum of GATA4 mutations associated with sporadic DCM remain unclear. In this study, the coding exons and exon-intron boundaries of the GATA4… CONTINUE READING

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