Prevalence and prognostic significance of acinar cell differentiation in pancreatic endocrine tumors.

@article{Yantiss2002PrevalenceAP,
  title={Prevalence and prognostic significance of acinar cell differentiation in pancreatic endocrine tumors.},
  author={Rhonda K. Yantiss and Hee-Kyung Chang and Francis A Farraye and Carolyn C. Compton and Robert D Odze},
  journal={The American journal of surgical pathology},
  year={2002},
  volume={26 7},
  pages={893-901}
}
We have noted that many histologically and immunohistochemically confirmed pancreatic endocrine tumors show immunophenotypic evidence of acinar cell differentiation, but the clinical relevance of this finding is unknown. We performed this study to evaluate the prevalence and prognostic significance of exocrine differentiation by immunohistochemistry in pancreatic endocrine tumors that do not show morphologic features of acinar cell differentiation. Routinely processed tissue sections from 87… CONTINUE READING

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