Prevalence and outcome of non-alcoholic fatty liver disease in adolescents and young adults undergoing weight loss surgery.

@article{Corey2014PrevalenceAO,
  title={Prevalence and outcome of non-alcoholic fatty liver disease in adolescents and young adults undergoing weight loss surgery.},
  author={Kathleen E Corey and Takara L. Stanley and Joseph Misdraji and Christina S Scirica and Janey S Pratt and Alison G Hoppin and Madhusmita Misra},
  journal={Pediatric obesity},
  year={2014},
  volume={9 5},
  pages={e91-3}
}
BACKGROUND/OBJECTIVE We evaluated the prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) in 27 adolescents referred for weight loss surgery (WLS). RESULTS On biopsy, 18 patients (66.7%) had NAFLD, and of those, 10 (37.0%) had NASH and 11 (40.7%) had fibrosis. Insulin, HbA1C and homeostatic model assessment of insulin resistance (HOMA-IR) were significantly higher in patients with NASH than those without NASH. Following WLS, 40% of patients with… CONTINUE READING