Prevalence and incidence of dermatitis herpetiformis: a 40‐year prospective study from Finland

@article{Salmi2011PrevalenceAI,
  title={Prevalence and incidence of dermatitis herpetiformis: a 40‐year prospective study from Finland},
  author={Teea Salmi and Kaisa Hervonen and Hannu Kautiainen and Patrick Collin and Timo Reunala},
  journal={British Journal of Dermatology},
  year={2011},
  volume={165}
}
Background  Dermatitis herpetiformis (DH) is an external manifestation of coeliac disease presenting with blistering rash and pathognomonic cutaneous IgA deposits. Better knowledge of subclinical forms and serological testing has resulted in a sharp increase in the incidence and prevalence of coeliac disease. 
Reduced mortality in dermatitis herpetiformis: a population‐based study of 476 patients
TLDR
Dermatitis herpetiformis is an extra‐intestinal manifestation of coeliac disease and most patients adhere to a life‐long gluten free diet (GFD), but knowledge in DH is scanty.
S2k guidelines (consensus statement) for diagnosis and therapy of dermatitis herpetiformis initiated by the European Academy of Dermatology and Venereology (EADV)
Dermatitis herpetiformis (DH) is a chronic, pruritic, gluten‐induced skin disorder characterized by subepidermal granular IgA deposition and a variable degree of enteropathy identical to that seen in
An Unusual Case of Dermatitis Herpetiformis
TLDR
Histopathologic findings, serology, and response to treatment rather than classical clinical findings and direct immunofluorescence supported the diagnosis of DH in this case.
Current Concepts of Dermatitis Herpetiformis.
TLDR
The treatment of choice for DH is a life-long gluten-free diet, which resolves the rash and enteropathy, increases quality of life, and offers a good long-term prognosis.
Dermatitis herpetiformis in children: a long‐term follow‐up study
TLDR
These figures indicate that in Finland, where the prevalence of DH is the highest reported (75 3 per 100 000 population), this disorder rarely appears in children, more than six times higher than the annual incidence of adult patients with DH and about 20 times lower than the incidence of childhood coeliac disease in Finland.
The Decreasing Prevalence of Severe Villous Atrophy in Dermatitis Herpetiformis: A 45-Year Experience in 393 Patients
TLDR
The trend toward milder small-bowel histology in DH suggests that a similar pattern could occur in the pool of undiagnosed celiac disease from which DH develops.
Incidence and Prevalence of Celiac Disease and Dermatitis Herpetiformis in the UK Over Two Decades: Population-Based Study
TLDR
A fourfold increase in the incidence of CD in the United Kingdom over 22 years is found, with large regional variations in prevalence, which could reflect differences in diagnosis between CD and DH and the possibility that diagnosing and treating CD prevents the development of DH.
Diagnostic Delay in Dermatitis Herpetiformis in a High-prevalence Area.
TLDR
It was showed that one-quarter of patients with DH currently have a diagnostic delay of 2 years or more, which is far from ideal.
Novel Advances in Dermatitis Herpetiformis
TLDR
The present issue addresses the recent advances of clinical, pathogenetic, and therapeutic aspects of DH, a complex disease where the skin represents a clue for the identification of a gluten-sensitive enteropathy.
The falling incidence and prevalence of dermatitis herpetiformis
  • L. Fry
  • Medicine
    The British journal of dermatology
  • 2011
TLDR
This study provides further insight into the relationship between coeliac disease and DH and finds that the age of presentation of DH has risen in men from 35 to 51 years and in women from 36 to 45 years, and the amount of cereal eaten annually per person has fallen.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 37 REFERENCES
Incidence and prevalence of dermatitis herpetiformis in western Sweden.
TLDR
The annual incidence of IgA-positive dermatitis herpetiformis during the years 1976-1981 in Gothenburg, Sweden, a city with approximately 430000 inhabitants, was estimated prospectively and probably represents the minimum overall prevalence rate.
Natural history of dermatitis herpetiformis in southern Sweden.
TLDR
A retrospective clinical survey of 96 patients with dermatitis herpetiformis in southern Sweden found that DH seems to be less active the later in life it starts, and many mild cases of DH were observed without a gluten-free diet.
Dermatitis herpetiformis: coeliac disease of the skin.
TLDR
Monozygotic twins, one with DH and the other with coeliac disease, show that environmental, not genetic, factors seem to be responsible for the development of the rash in DH.
Incidence of familial dermatitis herpetiformis
  • T. Reunala
  • Medicine
    The British journal of dermatology
  • 1996
TLDR
Analysis of the familial incidence of DH showed that 13·6% of parents, 18·7% of siblings and 14·0% of children were affected, a segregation pattern which fits well to a dominant mode of Mendelian inheritance.
Incidence and prevalence of dermatitis herpetiformis in a country in central Sweden, with comments on the course of the disease and IgA deposits as diagnostic criterion.
  • H. Moi
  • Medicine
    Acta dermato-venereologica
  • 1984
TLDR
In a defined area of 273 000 inhabitants in Central Sweden a total number of 125 patients with dermatitis herpetiformis were observed during the years 1974-1982, and the prevalence of DH in the area was 39.2 patients/100 000 inhabitants, which is much higher than previously reported.
Dermatitis herpetiformis in Finland.
TLDR
During a 3 1/2-year period, 492 patients with dermatitis herpetiformis visited the dermatological departments of Finnish hospitals, showing that DH is a rather common disease in Finland--much more so in Finland than in Britain.
Dermatitis herpetiformis: diagnosis, diet and demography.
TLDR
It is concluded that a gluten free diet is of therapeutic benefit in dermatitis herpetiformis and that spontaneous remission is uncommon in those not on a diet.
Clinics of coeliac disease in children in the 2000s
TLDR
The clinical picture of patients with coeliac disease and the change in its presentation over the past decades are described.
Dermatitis herpetiformis: a review of 119 cases
TLDR
Between 1954 and 1980 119 cases of dermatitis herpetiformis have been seen, and two out of twenty patients examined had anti‐reticulin antibodies and a gluten‐free diet is advocated for all patients.
Increasing prevalence of coeliac disease over time
Background  The number of coeliac disease diagnoses has increased in the recent past and according to screening studies, the total prevalence of the disorder is around 1%.
...
1
2
3
4
...