Prevalence and genetic location of non-transferable trimethoprim resistant dihydrofolate reductase genes in South African commensal faecal isolates.

@article{Adrian1995PrevalenceAG,
  title={Prevalence and genetic location of non-transferable trimethoprim resistant dihydrofolate reductase genes in South African commensal faecal isolates.},
  author={Peter V. Adrian and Christopher J. Thomson and Keith P. Klugman and Sebastian Giles Becket Amyes},
  journal={Epidemiology and infection},
  year={1995},
  volume={115 2},
  pages={255-67}
}
In a recent survey of trimethoprim resistance, 357 Gram-negative aerobic organisms were isolated from healthy volunteers from rural and urban populations in South Africa. Trimethoprim resistance did not transfer to an Escherichia coli J62-2 recipient strain by conjugation in a liquid mating in 161 (45.1%) of the isolates. These isolates which did not… CONTINUE READING