Prevalence and clinical significance of anti-phospholipid antibodies in multiple sclerosis: a study of 89 patients.

@article{Roussel2000PrevalenceAC,
  title={Prevalence and clinical significance of anti-phospholipid antibodies in multiple sclerosis: a study of 89 patients.},
  author={V Roussel and Feng-ming Yi and Marie Odile Jauberteau and C Couderq and Catherine Lacombe and V Michelet and Roger Gil and Philippe P Couratier and Jean-michel Vallat and J. L. Preud'homme},
  journal={Journal of autoimmunity},
  year={2000},
  volume={14 3},
  pages={259-65}
}
The prevalence of serum anti-phospholipid antibodies (aPL) was evaluated in multiple sclerosis (MS) patients to search for a possible association with a distinct form of the disease. Anti-cardiolipin antibodies (Ab) (aCL) and anti-beta 2 glycoprotein I Ab (abeta2GPI) were measured together with antinuclear Ab (ANA), anti-double-stranded DNA Ab (anti-ds DNA) and anti-myelin Ab in 89 patients. Twenty-nine (32.6%) patients had serum aPL, 19xaCL (15 of the IgG and four of the IgM isotype), 14… CONTINUE READING