Prevalence and clinical relevance of local allergic rhinitis

@article{Rondn2012PrevalenceAC,
  title={Prevalence and clinical relevance of local allergic rhinitis},
  author={Carmen Rond{\'o}n and Paloma Campo and Luisa Galindo and Natalia Blanca-L{\'o}pez and Maria Salas Cassinello and Jos{\'e} Luis Rodr{\'i}guez-Bada and M J Torres and Miguel Blanca},
  journal={Allergy},
  year={2012},
  volume={67}
}
Evidence demonstrates the existence of local allergic rhinitis (LAR) in nonatopic patients, although its prevalence in the rhinitis population remains unknown. The aim, therefore, of this study was to evaluate the prevalence, clinical characteristics, and severity of LAR in a Spanish rhinitis population, compared with patients having classical allergic rhinitis (AR) with systemic atopy or nonallergic rhinitis (NAR). 

Local Allergic Rhinitis.

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This review aims to comprehensively summarize the current knowledge on LAR and address unmet needs in the areas of disease diagnosis and treatment.

Evidences for Local Allergic Rhinitis

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References

SHOWING 1-10 OF 30 REFERENCES

Atypical nasal challenges in patients with idiopathic rhinitis: more evidence for the existence of allergy in the absence of atopy?

TLDR
This study compares detailed nasal challenge results obtained from patients with idiopathic rhinitis to those of atopic and normal controls.

Seasonal idiopathic rhinitis with local inflammatory response and specific IgE in absence of systemic response

TLDR
N nasal mucosa inflammation, the presence of nasal specific‐IgE and the response to nasal allergen provocation test (NAPT) in patients with seasonal IR who presented symptoms only in spring are examined.

Evidence for an inflammatory pathophysiology in idiopathic rhinitis

TLDR
This work has shown that persistent idiopathic rhinitis has a Th2 type inflammatory pathology mediated by IgE and mast cells, and the disease is classified as being non‐allergic on the basis of negative serum IgE radioallergosorbent assay (RAST) and skin prick tests.

‘Entopy’: localized mucosal allergic disease in the absence of systemic responses for atopy

TLDR
The Th2 immune response in the nasal mucosa of subjects with allergic rhinitis is mediated by allergen‐specific IgE, and subjects with similar histological nasal mucosal features differ in being defined as non‐allergic because they have negative atopic responses.

Allergic Rhinitis and its Impact on Asthma (ARIA)

TLDR
A new subdivision of allergic rhinitis is proposed and suggests evidence-based management of the disease using a stepwise approach and it is proposed that allergic patients are treated globally to combine treatment of upper and lower airway disease.

Differences between allergic and nonallergic rhinitis in a large sample of adolescents and adults

TLDR
Differences between allergic rhinitis (AR) and nonallergic rhINitis (NAR) in a large community‐based sample of Danish adolescents and adults are described.

Immediate and dual response to nasal challenge with Dermatophagoides pteronyssinus in local allergic rhinitis

  • S. LópezC. Rondón M. Blanca
  • Medicine, Biology
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
  • 2010
Background Local allergic rhinitis (LAR) is characterized by in situ production of specific IgE (sIgE) antibodies and a positive response to a nasal allergen provocation test (NAPT) in the absence of

Relationships between rhinitis and asthma

TLDR
Although the nasal and bronchial mucosa present similarities, there are also differences which might suggest that rhinitis and asthma are two different airway diseases.

Update on nonallergic rhinitis.

  • R. SettipaneP. Lieberman
  • Medicine
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
  • 2001