Prevalence and clinical features of HTLV neurologic disease in the HTLV Outcomes Study.

@article{Orland2003PrevalenceAC,
  title={Prevalence and clinical features of HTLV neurologic disease in the HTLV Outcomes Study.},
  author={Jennie R Orland and John W. Engstrom and Joy L Fridey and Ronald A. Sacher and John W. T. Smith and Caitlin M Nass and George Garratty and Bruce H Newman and Don Smith and Binyan Wang and Katharine Loughlin and Edward Laurence Murphy},
  journal={Neurology},
  year={2003},
  volume={61 11},
  pages={1588-94}
}
BACKGROUND Almost 20 years after its discovery, the prevalence and clinical course of human T-lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM, also known as tropical spastic paraparesis [TSP]) remain poorly defined. Whereas the causative association of HTLV-I and HAM/TSP is generally recognized, controversy still surrounds the relationship between HTLV-II and HAM/TSP. METHODS The HTLV Outcomes Study (HOST-formerly Retrovirus Epidemiology Donor Study [REDS]) is a prospective… CONTINUE READING

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