Prevalence and Risk Factors for Herpes Simplex Virus Type 2 Infection Among Pregnant Women in Israel

  title={Prevalence and Risk Factors for Herpes Simplex Virus Type 2 Infection Among Pregnant Women in Israel},
  author={Michael Dan and Oscar Sadan and Marek Glezerman and David P Raveh and Zmira Samra},
  journal={Sexually Transmitted Diseases},
Background Although usually a nuisance to the adult patient, herpes simplex virus type 2 (HSV-2) infection can have devastating consequences on the infected newborn. It is thus important to document the prevalence and risk factors of this infection among pregnant women in a defined population. The availability of the new type-specific assays that provide accurate serologic results prompted us to study the seroprevalence of HSV-2 infection among pregnant women in Israel. Study Design In a cross… 
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In pregnant women, HSV-1 seroprevalence was higher than in Western Europe but similar to that in Eastern Europe, andHSV-2 seropresence was within European ranges, both of which were lower than in the USA.
Genital Infection with Herpes Simplex Virus Types 1 and 2 in Women from Natal, Brazil
The genital infection by HSV-2 was higher in women with changed colposcopy and/or cytology, and it was associated with ethnicity, marital status, and number of sexual partners, and the prevalence of HSV/HSV-1 was higher than that observed in both pregnant and nonpregnant women.
Seroprevalence and Co-Infection of Human Immunodeficiency Virus (HIV) and Herpes Simplex Virus (HSV) Among Pregnant Women in Lokoja, North-Central Nigeria
Advocacy and publicity to raise awareness of the potential public health impact of HSV and HIV co-infection in Nigeria, where anti-HSV testing is not generally performed in all populations, is recommended.
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The HSV-2 seroprevalence was twice as high in women than in men and increased with age in both sexes, and similar to that reported from high-prevalence countries in Europe and the USA; it also contributes to the burden GUD among both sexes.
Association between HSV-2 and HIV serostatus in pregnant women of known HIV serostatus attending Mulago hospital antenatal clinic, Kampala, Uganda.
The proportion of HSV-2 was higher in HIV-positive cases than in the HIV negative controls, and was significantly increased to 5.32 among cases when adjustment was done for age, education, marital status, religion, age at first sexual experience, lifetime partners, type of earning, and whether the mother involved the partner in seeking treatment for sexually transmitted diseases.
Seroprevalence and associated factors of HSV-2 infection among general population in Shandong Province, China
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Socio-demographic and behavioral correlates of herpes simplex virus type 1 and 2 infections and co-infections among adults in the USA.


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The possible availability of an HSV-2 vaccine that is able to protect over 70% of women offers the best hope for control of genital herpes.
Seroprevalence Study of Herpes Simplex Virus Type 2 among Pregnant Women in Germany Using a Type-Specific Enzyme Immunoassay
Control studies with a type-common HSV assay measuring antibodies to HSV1 and HSV-2 revealed that 20.7% of pregnant women were seronegative for HSV antibodies and are therefore at risk of acquiring primary genital HSV infection of either type.
Seroprevalences of Herpes Simplex Virus Type 1 and Type 2 Among Pregnant Women in the Netherlands
The seroprevalence of HSV-1 andHSV-2 antibodies among pregnant women in the Netherlands shows significant geographical differences, which were attributed to ethnical variation, however, the epidemiologic differences did not correlate with the incidence of neonatal herpes inThe Netherlands.
Serological evaluation of herpes simplex virus type 1 and type 2 infections in pregnancy.
Serological assays for gG2 antibodies were readily distinguished from HSV-1 gG1 IgG antibodies by the glycoprotein gG ELISAs, and should guard against the decline of specific antibodies during pregnancy.
Antenatal Seroprevalence of Herpes Simplex Virus Type 2 (HSV-2) in Canadian Women: HSV-2 Prevalence Increases Throughout the Reproductive Years
TheHSV-2 seroprevalence among pregnant women in British Columbia is similar to that in the United States and other countries, which may relate to continued transmission, an age cohort effect, orboth.
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    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
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Prevalence and correlates of herpes simplex infections. The population-based AIDS in Multiethnic Neighborhoods Study.
HSV-2 antibodies were associated with a lower frequency of HSV-1 antibodies among homosexual men infected with the human immunodeficiency virus, and were most common among Hispanics not born in the United States.
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The prospective risk of a woman with secondary type genital herpes virus infection to transmit the infection to her baby at the time of delivery is small and the silent nature of the majority of maternal infections makes prevention difficult.
A seroepidemiologic survey of the prevalence of herpes simplex virus type 2 infection in the United States.
It is concluded that the prevalence of HSV-2 infection in the United States is higher than has previously been recognized and that many infections with this sexually transmitted virus may be subclinical.
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Nearly 40 percent of newly acquired HSV-2 infections and nearly two thirds of new HSv-1 infections are symptomatic, and among sexually active adults, new genital HSVs type 1 and 2 infections are as common as new oropharyngeal HSV -1 infections.