Prevalence and Localization of Pulmonary Embolism in Unexplained Acute Exacerbations of COPD: A Systematic Review and Meta‐analysis

@article{Aleva2017PrevalenceAL,
  title={Prevalence and Localization of Pulmonary Embolism in Unexplained Acute Exacerbations of COPD: A Systematic Review and Meta‐analysis},
  author={Floor E Aleva and Lucas W L M Voets and Sami O. Simons and Quirijn de Mast and Andre J. van der Ven and Yvonne F. Heijdra},
  journal={Chest},
  year={2017},
  volume={151},
  pages={544–554}
}
BACKGROUND: Patients with COPD experience episodes of increased inflammation, so‐called acute exacerbations of COPD (AE‐COPD). In 30% of AE‐COPD cases, no clear cause is found. Since there is well‐known cross talk between inflammation and thrombosis, the objectives of this study were to determine the prevalence, embolus localization, clinical relevance, and clinical markers of pulmonary embolism (PE) in unexplained AE‐COPD. METHODS: A systematic search was performed using MEDLINE and EMBASE… 

Paper Mentions

Interventional Clinical Trial
AECOPD increases the risk of VTE.VTE prevention is a long way to go for high-risk VTE patients in China.The incidence of AECOPD complicated with VTE in Asian population is high… 
ConditionsAcute Exacerbation Copd, Venous Thromboembolism
InterventionDrug
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A diagnosis of PE should be considered in patients with exacerbation severe enough to warrant hospitalization, especially in those with an intermediate-to-high pretest probability of PE.
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