Prevalence and Laboratory Profile of Hepatitis B Virus Co-infected Nigerian Children with Human Immunodeficiency Virus

  title={Prevalence and Laboratory Profile of Hepatitis B Virus Co-infected Nigerian Children with Human Immunodeficiency Virus},
  author={Stephen Oguche and Augustine Odo Ebonyi and Es Okpe and Esther Simon Yiltok and Martha O. Ochoga and Joseph A Anejo-Okopi and Oche Ochai Agbaji and John A. Idoko and Prosper Okonkwo and Phyllis J Kanki},
  journal={International Journal of Tropical Disease \& Health},
  • S. Oguche, A. Ebonyi, P. Kanki
  • Published 10 January 2014
  • Medicine, Biology
  • International Journal of Tropical Disease & Health
Aims: To determine the prevalence of HBV co-infection in HIV-infected children and compare the baseline laboratory profile of mono-infected and co-infected patients. Study Design: This was a retrospective cohort study. Place and Duration of Study: AIDS Prevention Initiative in Nigeria (APIN)-supported HIV clinic of Jos University Teaching Hospital, Jos, Nigeria between January 2008 and December 2012. Original Research Article International Journal of TROPICAL DISEASE & Health, 4(7): 773-781… 

Tables from this paper

Assessment of CD 4 Count and Some Haematological Parameters of HIV Positive Patients Co-infected with Hepatitis B Virus in Osun State , Nigeria
HBV exist among HIV positive patients living in Osun State, Nigeria, with a prevalence rate of 16.5%.
Prevalence of and risk factors for hepatitis B and C viral co-infections in HIV infected children in Lagos, Nigeria
The prevalence of HBV and or HCV infection among HIV-infected children is similar to the prevalence among HIV naïve children, suggesting that HIV- infected children are not more predisposed to viral hepatitis than healthy children.
Hepatitis B Virus and Human Immunodeficiency Virus Infections among Health Care Workers in Some Health Care Centers in Benue State, Nigeria
There is need to scale up vaccination coverage for HBV and upgrade the medical facilities especially in rural health care centers as well as intensification of programmes targeting safety and prevention for precautions.
Prevalence of Chronic Liver Diseases Caused by HBV and HCV in Nigeria in Comparison with European Countries
Based on available data, there is a need for a national program on hepatitis B and C so as to reduce the incidence rate and the total burden of liver disease in Nigeria.


Prevalence and Clinical and Immunoviralogical Profile of Human Immunodeficiency Virus-Hepatitis B Coinfection among Children in an Antiretroviral Therapy Programme in Benue State, Nigeria
A high seroprevalence of HBV among this cohort of HIV-infected children contributes to the calls for pre-ART screening for HBV and the necessary paradigm shift in the ART nucleoside backbone to include agent(s) more dually effective against HIV and HBV.
HIV co-infection with hepatitis B and C viruses among Nigerian children in an antiretroviral treatment programme
The rate of HIV co-infection with hepatitis B and C in children in Nigeria is significant and HIV-infected children should be screened for these viruses.
Seroprevalence of hepatitis B and C viral co-infections among children infected with human immunodeficiency virus attending the paediatric HIV care and treatment center at Muhimbili National Hospital in Dar-es-Salaam, Tanzania
The high seroprevalence of hepatitis co- Infection in HIV infected children attending the Paediatrics HIV CTC at the MNH calls for routine screening of hepatitis viral co-infection and modification in the management of HIV infectedChildren.
Hepatitis C Virus and Human Immunodeficiency Virus-I (HIV) Co-Infection in Children in Benin City, Nigeria.
The study assessed the incidence of Hepatitis C virus (HCV) infection and co — infection with Human Immunodeficiency virus - 1 (HIV) amongst children between the ages of 0 — 17 years in Benin City, Nigeria and found only one child tested positive to HCV, giving a prevalence rate of 0.25%.
Frequent occurrence of chronic hepatitis B virus infection among West African HIV type-1-infected children.
  • F. Rouet, M. Chaix, P. Msellati
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2008
In sub-Saharan Africa, children with chronic hepatitis B and who are treated with 3TC-based HAART are at risk of developing 3TC resistance, and further studies are required to guide the management of HBV-HIV-1-coinfected children.
Prevalence of Hepatitis B co-infection amongst HIV infected children attending a care and treatment centre in Owerri, South-eastern Nigeria
Though this study shows a low prevalence of Hepatitis B co infection in HIV infected children in Owerri, reduction of the rate is still strongly desirable and can be achieved by strengthing the uptake of hepatitis B vaccine as part of the routine childhood immunization programme.
Rates and impact of hepatitis on human immunodeficiency virus infection in a large African cohort.
High rates of HBV and HCV infections were found in this HIV cohort in Nigeria, and CD4 recovery was significantly diminished in patients with HBV co-infection.
Some Laboratory Features of HIV Infected Nigerian Children Co-Infected with Hepatitis B and C
Screening for HBV may require more than testing for only HBsAg as HBV infection may be present in the setting of negative HBs ag, thus there is need for HIV infected children to be screened for hepatitis B and C.
Hepatitis B and Hepatitis C Seroprevalence in Children Receiving Antiretroviral Therapy for Human Immunodeficiency Virus-1 Infection in China, 2005-2009
The high prevalence of HBV and HCV coinfection in HIV-infected children in China receiving ART demands routine screening for viral hepatitis coinfections, intensive prevention of childhood HBV or hepatitis C virus transmission, and modification of the management of pediatric HIV infection.
Hepatitis B and C virus co-infection in Nigerian patients with HIV infection.
This low frequency of HIV/HCV co-infection is probably due to the uncommon intravenous drug abuse in this population of HIV-infected patients.