Prevalence and Characteristics of Pain Induced by Percutaneous Liver Biopsy

@article{Eisenberg2003PrevalenceAC,
  title={Prevalence and Characteristics of Pain Induced by Percutaneous Liver Biopsy},
  author={Elon Eisenberg and M Konopniki and E Veitsman and Rimma Kramskay and Diana Gaitini and Yaacov Baruch},
  journal={Anesthesia \& Analgesia},
  year={2003},
  volume={96},
  pages={1392-1396}
}
Percutaneous needle liver biopsy is an important procedure for the diagnosis and evaluation of liver disease and is frequently associated with pain. In this prospective study, we investigated the prevalence and characteristics of this pain syndrome. Fifty-four subjects, who underwent liver biopsy under ultrasound guidance, received 5 mg of diazepam orally 1 h before the procedure and local infiltration with 10 mL of 2% lidocaine just before needle insertion. Outcome measures included the visual… 
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TLDR
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Subcapsular anesthesia is a well-tolerated procedure compared to a pericapsular procedure and the application of a subcapsular anesthetic with a subcostal approach was reported to result in the lowest pain and greatest patient comfort.
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Ethnicity has an important role in the development of pain after US-guided percutaneous liver biopsy and has a significant impact on willingness to repeat the procedure.
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CT- and US- guided percutaneous biopsies are associated with low levels of pain that are generally well tolerated by patients irrespective of the targeted organ.
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