Pretreatment with pentoxifylline attenuates lung injury induced by intestinal ischemia/reperfusion in rats.

@article{Marqui2011PretreatmentWP,
  title={Pretreatment with pentoxifylline attenuates lung injury induced by intestinal ischemia/reperfusion in rats.},
  author={Carlos Eduardo Marqui and Helga Cristina Almeida da Silva and David Ferez and S{\^a}mia Santos Cavassani and Juliana Britto Moraes and Danielle Aparecida Marino da Silva and Ricardo Santos Sim{\~o}es and Caroline Aparecida Lopes and Murched Omar Taha and Itamar Souza de Oliveira-J{\'u}nior},
  journal={Acta cirurgica brasileira},
  year={2011},
  volume={26 6},
  pages={438-44}
}
PURPOSE To investigate the protective effect of pentoxifylline against the lung injury observed after intestinal ischemia (I) followed by a period of reperfusion (R). METHODS Twenty-eight male Wistar rats were equally divided into 4 experimental groups and operated under ketamine-xylazine anesthesia. (1) Sham: falsely-operated animals; (2) SS+IR: intestinal ischemia was accomplished by clipping the superior mesenteric artery during 60 minutes, with an administration of a standard volume of… CONTINUE READING

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