Pretreatment with neem (Azadirachta indica) leaf preparation in swiss mice diminishes leukopenia and enhances the antitumor activity of cyclophosphamide

@article{Ghosh2006PretreatmentWN,
  title={Pretreatment with neem (Azadirachta indica) leaf preparation in swiss mice diminishes leukopenia and enhances the antitumor activity of cyclophosphamide},
  author={Diptendu Ghosh and A. Bose and Enamul Haque and R. Baral},
  journal={Phytotherapy Research},
  year={2006},
  volume={20}
}
Cancer chemotherapy is associated with several life threatening complications, including bone marrow suppression and leucopenia. To overcome this problem, colony stimulating factor (CSF), granulocyte colony stimulating factor (GCSF) and granulocyte macrophage colony stimulating factor (GMCSF), can be used, however, these therapeutics are expensive and have several disadvantages, including tumor growth promoting activities. This study attempted to use an immunostimulatory neem (Azadirachta… Expand
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NLP-activated NK and NK-T cells in mice may regulate tumor cell cytotoxicity by enhancing the secretion of different cytotoxic cytokines. Expand
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