Pretreatment neutrophil-to-lymphocyte ratio is associated with advanced pathologic tumor stage and increased cancer-specific mortality among patients with urothelial carcinoma of the bladder undergoing radical cystectomy.

@article{Viers2014PretreatmentNR,
  title={Pretreatment neutrophil-to-lymphocyte ratio is associated with advanced pathologic tumor stage and increased cancer-specific mortality among patients with urothelial carcinoma of the bladder undergoing radical cystectomy.},
  author={Boyd R. Viers and Stephen Anthony Boorjian and Igor Frank and Robert F. Tarrell and Prabin Thapa and Robert Jeffrey Karnes and Robert Thompson and Matthew K. Tollefson},
  journal={European urology},
  year={2014},
  volume={66 6},
  pages={1157-64}
}
BACKGROUND Pretreatment neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that has been associated with adverse survival in a variety of malignancies. However, the relationship between NLR and oncologic outcomes following radical cystectomy (RC) for urothelial carcinoma of the bladder (UCB) has not been well studied. OBJECTIVE To evaluate the association of preoperative NLR with clinicopathologic outcomes following RC. DESIGN, SETTING, AND PARTICIPANTS We identified… CONTINUE READING
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