Pretreatment apparent diffusion coefficient of the primary lesion correlates with local failure in head-and-neck cancer treated with chemoradiotherapy or radiotherapy.

@article{Hatakenaka2011PretreatmentAD,
  title={Pretreatment apparent diffusion coefficient of the primary lesion correlates with local failure in head-and-neck cancer treated with chemoradiotherapy or radiotherapy.},
  author={Masamitsu Hatakenaka and Katsumasa Nakamura and Hidetake Yabuuchi and Yoshiyuki Shioyama and Yoshio Matsuo and Kayoko Ohnishi and Shunya Sunami and Takeshi Kamitani and Taro Setoguchi and Takashi Yoshiura and Torahiko Nakashima and Kei Nishikawa and Hiroshi Honda},
  journal={International journal of radiation oncology, biology, physics},
  year={2011},
  volume={81 2},
  pages={
          339-45
        }
}
PURPOSE This study was performed to evaluate whether the apparent diffusion coefficient (ADC) of a primary lesion correlates with local failure in primary head-and-neck squamous cell carcinoma (HNSCC) treated with chemoradiotherapy or radiotherapy. METHODS AND MATERIALS We retrospectively studied 38 patients with primary HNSCC (12 oropharynx, 20 hypopharynx, 4 larynx, 2 oral cavity) treated with chemoradiotherapy or radiotherapy with radiation dose to gross tumor volume equal to or over 60 Gy… CONTINUE READING

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