Pretreatment apoptosis in carcinoma of the cervix correlates with changes in tumour oxygenation during radiotherapy

@article{Sheridan2000PretreatmentAI,
  title={Pretreatment apoptosis in carcinoma of the cervix correlates with changes in tumour oxygenation during radiotherapy},
  author={Mairead Sheridan and Catharine M. L. West and Rachel A. Cooper and Ian James Stratford and John P. Logue and S. E. Davidson and R. Douglas Hunter},
  journal={British Journal of Cancer},
  year={2000},
  volume={82},
  pages={1177 - 1182}
}
A relationship between hypoxia and apoptosis has been identified in vitro and in experimental tumours. The aim of this study was to investigate the relationship between apoptosis, hypoxia and the change in oxygenation during radiotherapy in human squamous cell carcinoma of the cervix. Forty-two patients with locally advanced disease underwent pretreatment evaluation of tumour oxygenation using an Eppendorf computerized microneedle electrode. Twenty-two of these patients also had a second… CONTINUE READING
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