Preterm labor: One syndrome, many causes

@article{Romero2014PretermLO,
  title={Preterm labor: One syndrome, many causes},
  author={Roberto Romero and Sudhansu K Dey and Susan J. Fisher},
  journal={Science},
  year={2014},
  volume={345},
  pages={760-765}
}
Preterm birth is associated with 5 to 18% of pregnancies and is a leading cause of infant morbidity and mortality. Spontaneous preterm labor, a syndrome caused by multiple pathologic processes, leads to 70% of preterm births. The prevention and the treatment of preterm labor have been long-standing challenges. We summarize the current understanding of the mechanisms of disease implicated in this condition and review advances relevant to intra-amniotic infection, decidual senescence, and… CONTINUE READING
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