Pretargeted gamma imaging of murine metastatic melanoma lung lesions with bispecific antibody and radiolabeled polymer drug conjugates.

Abstract

INTRODUCTION Bispecific monoclonal antibodies (bsMAbs) have been developed as a pretargeting tool to reduce background activity, thereby increasing target to background (T : B) ratios. To enhance visualization of small lesions in vivo, we have used the pretargeting approach of bsMAb and negatively charged polymers radiolabeled with high-specific… (More)
DOI: 10.1097/MNM.0b013e32834af77b

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@article{Gada2011PretargetedGI, title={Pretargeted gamma imaging of murine metastatic melanoma lung lesions with bispecific antibody and radiolabeled polymer drug conjugates.}, author={Keyur S. Gada and Vishwesh Patil and Rajiv Panwar and Stan Majewski and Yared Tekabe and Ban-An Khaw}, journal={Nuclear medicine communications}, year={2011}, volume={32 12}, pages={1231-40} }