Presynaptic modulation of tonic and respiratory inputs to cardiovagal motoneurons by substance P.


Substance P (SP) has been implicated in vagal control of heart rate and cardiac functions, but the mechanisms of SP actions on cardiac vagal activity remain obscure. The present study has investigated the effects of SP on the synaptic inputs of preganglionic cardiovagal motoneurons (CVNs) in brainstem slices of neonatal rat. Whole-cell voltage-clamp… (More)
DOI: 10.1016/j.brainres.2009.05.056