Presynaptic clathrin levels are a limiting factor for synaptic transmission.


To maintain communication, neurons must recycle their synaptic vesicles with high efficiency. This process places a huge burden on the clathrin-mediated endocytic machinery, but the consequences of this are poorly understood. We found that the amount of clathrin in a presynaptic terminal is not fixed. During stimulation, clathrin moves out of synapses as a… (More)
DOI: 10.1523/JNEUROSCI.5081-13.2014


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@article{LpezMurcia2014PresynapticCL, title={Presynaptic clathrin levels are a limiting factor for synaptic transmission.}, author={Francisco Jos{\'e} L{\'o}pez-Murcia and Stephen J Royle and Artur Llobet}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={2014}, volume={34 25}, pages={8618-29} }