Presynaptic autoinhibition of the electrically evoked dopamine release studied in the rat olfactory tubercle byin vivo electrochemistry

  title={Presynaptic autoinhibition of the electrically evoked dopamine release studied in the rat olfactory tubercle byin vivo electrochemistry},
  author={Marie-Françoise Suaud-Chagny and J. Ponec and François G. Gonon},

Prolonged and Extrasynaptic Excitatory Action of Dopamine Mediated by D1 Receptors in the Rat Striatum In Vivo

  • F. Gonon
  • Biology
    The Journal of Neuroscience
  • 1997
The spatiotemporal characteristics of the dopaminergic transmission mediated by D1 receptors were investigated in vivo. For this purpose dopamine (DA) release was evoked in the striatum of

Inhibition of Dopamine Release Via Presynaptic D2 Receptors: Time Course and Functional Characteristics In Vivo

Dopamine release was evoked in the striatum of anesthetized mice by electrical stimulation of the medial forebrain bundle and was continuously monitored by amperometry using carbon fiber electrodes and autoinhibition eliciting by one burst transiently attenuates further dopamine release elicited by tonic activity.

Endogenous neurotensin down‐regulates dopamine efflux in the nucleus accumbens as revealed by SR‐142948A, a selective neurotensin receptor antagonist

The hypothesis that endogenous neurotensin could exert a negative control on mesolimbic dopamine efflux is strengthened by the results of this study.



Comparative dopamine-cholinergic mechanisms in the olfactory tubercle and the striatum: effects of metoclopramide.

The olfactory tubercle (OT) is a limbic structure containing high dopamine (DA) and acetylcholine (ACh) concentrations and the effects of metoclopramide in the OT and the nucleus caudate (striatum) were performed.

Pharmacological profile of dopamine receptor agonists as studied by brain dialysis in behaving rats.

Investigation of the effect of various dopamine (DA) receptor agonists on the release and metabolism of DA in two terminal dopaminergic areas in freely moving rats finds inhibition of DA release appears related to the ability of the various agonists to stimulate D-2 rather than D-1 receptors.

Drug-Induced Changes in the Release of 3H-Monoamines from Field Stimulated Rat Brain Slices

It seems probable from the present results that the turnover changes found in vivo after these drugs may at least partly also be due to a local effect at the central monoamine synapse, possibly via a negative feed-back mechanism.

Frequency‐Dependent Release of Acetylcholine and Dopamine From Rabbit Striatum: Its Modulation by Dopaminergic Receptors

The results suggest that the release of DA and ACh is regulated by dopaminergic receptors and that at high frequencies the slope of the curves is modified by activation of pre‐ and postsynaptic DA receptors.