Presynaptic adenosine A₁ receptors modulate excitatory transmission in the rat basolateral amygdala.

@article{Rau2014PresynapticAA,
  title={Presynaptic adenosine A₁ receptors modulate excitatory transmission in the rat basolateral amygdala.},
  author={Andrew R Rau and Olusegun J. Ariwodola and J. L. Weiner},
  journal={Neuropharmacology},
  year={2014},
  volume={77},
  pages={465-74}
}
The basolateral amygdala (BLA) plays an integral role in the etiology of anxiety disorders and alcoholism. Although much is known about the intrinsic circuitry that governs BLA excitability, our understanding of the neuromodulators that control BLA excitation is incomplete. In many brain regions, adenosine (ADO) regulates neuronal excitability, primarily via A₁ receptor inhibition of glutamate release, and basal adenosinergic tone is high enough to tonically inhibit neuronal excitation… CONTINUE READING

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