Presynaptic Protein Interactions that Regulate Synaptic Strength at Crayfish Neuromuscular Junctions.

@inproceedings{Prashad2014PresynapticPI,
  title={Presynaptic Protein Interactions that Regulate Synaptic Strength at Crayfish Neuromuscular Junctions.},
  author={Rene Christopher Prashad},
  year={2014}
}
Synapses vary widely in the probability of transmitter release. For instance, in response to an action potential the phasic synapses of the crayfish have a 100-1000-fold higher release probability than tonic synapses. The difference in release probability is attributed to differences in the exocytotic machinery such as the degree of “zippering” of the trans-SNARE (Soluble Nethylmaleimide-sensitive factor Attachment protein REceptor) complex. I used physiological and molecular approaches to… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 376 REFERENCES

Complexin-I is required for high-fidelity transmission at the endbulb of Held auditory synapse.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2009
VIEW 24 EXCERPTS
HIGHLY INFLUENTIAL

Complexin II plays a positive role in Ca2+-triggered exocytosis by facilitating vesicle priming.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2008
VIEW 21 EXCERPTS
HIGHLY INFLUENTIAL

Complexin and Ca2+ stimulate SNARE-mediated membrane fusion

  • Nature Structural &Molecular Biology
  • 2008
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL