Presynaptic Modulation of Spontaneous Inhibitory Postsynaptic Currents by Gamma-hydroxybutyrate in the Substantia Nigra Pars Compacta

@article{Brancucci2004PresynapticMO,
  title={Presynaptic Modulation of Spontaneous Inhibitory Postsynaptic Currents by Gamma-hydroxybutyrate in the Substantia Nigra Pars Compacta},
  author={Alfredo Brancucci and Nicola Berretta and Nicola Biagio Mercuri and Walter Francesconi},
  journal={Neuropsychopharmacology},
  year={2004},
  volume={29},
  pages={537-543}
}
The regulation of GABA release from the inhibitory input to dopamine cells in the substantia nigra pars compacta (SNc) plays a key role in different reward-related behaviors. Gamma-hydroxybutyrate (GHB) has therapeutical properties in various psychiatric disorders, especially in alcohol abuse. GHB is also used as a drug of abuse, which induces sedation and euphoria. Using whole-cell patch-clamp recordings, we studied the effects of GHB on GABA release in the SNc by recording spontaneous… CONTINUE READING
11 Extracted Citations
54 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 11 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 54 references

Similar Papers

Loading similar papers…