Presynaptic K+ channels: electrifying regulators of synaptic terminal excitability.

  title={Presynaptic K+ channels: electrifying regulators of synaptic terminal excitability.},
  author={Paul D Dodson and Ian D. Forsythe},
  journal={Trends in neurosciences},
  volume={27 4},
Potassium channels are crucial regulators of neuronal excitability, setting resting membrane potentials and firing thresholds, repolarizing action potentials and limiting excitability. Although most of our understanding of K+ channels is based on somatic recordings, there is good evidence that these channels are present in synaptic terminals. In recent years the improved access to presynaptic compartments afforded by direct recording techniques has indicated diverse roles for native K+ channels… CONTINUE READING

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