Presynaptic Action Potential Amplification by Voltage-Gated Na+ Channels in Hippocampal Mossy Fiber Boutons

Abstract

Action potentials in central neurons are initiated near the axon initial segment, propagate into the axon, and finally invade the presynaptic terminals, where they trigger transmitter release. Voltage-gated Na(+) channels are key determinants of excitability, but Na(+) channel density and properties in axons and presynaptic terminals of cortical neurons… (More)
DOI: 10.1016/j.neuron.2004.12.048

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@article{Engel2005PresynapticAP, title={Presynaptic Action Potential Amplification by Voltage-Gated Na+ Channels in Hippocampal Mossy Fiber Boutons}, author={Dominique Engel and Peter Jonas}, journal={Neuron}, year={2005}, volume={45}, pages={405-417} }