Presynaptic α-adrenoceptors and the action of tricyclic antidepressant drugs in behavioural despair in rats

Abstract

The influence of the α-adrenolytics, yohimbine and phentolamine, given in low doses thought to block presynaptic α-adrenoceptors, on the action of the tricyclic antidepressants imipramine, nortriptyline and amitriptyline in the behavioural despair test was investigated in Wistar rats. Antidepressant drugs given in a single dose or for 2 weeks reduced… (More)
DOI: 10.1007/BF00434407

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@article{ebrowskaupina1980PresynapticA, title={Presynaptic α-adrenoceptors and the action of tricyclic antidepressant drugs in behavioural despair in rats}, author={Iwona Żebrowska-Łupina}, journal={Psychopharmacology}, year={1980}, volume={71}, pages={169-172} }