Presumed common source outbreaks of hepatitis A in an endemic area confirmed by limited sequencing within the VP1 region.

@article{ArauzRuiz2001PresumedCS,
  title={Presumed common source outbreaks of hepatitis A in an endemic area confirmed by limited sequencing within the VP1 region.},
  author={Patricia Arauz-Ruiz and Lena Sundqvist and Zacharias Garcia and Lizeth Taylor and Kirsten Vison{\'a} and Hel{\'e}ne Norder and Lars O. Magnius},
  journal={Journal of medical virology},
  year={2001},
  volume={65 3},
  pages={449-56}
}
Hepatitis A virus isolates from anti-HAV IgM positive sera of 70 hepatitis cases in two outbreaks and 216 other cases in Central America, 136 sporadic cases and 53 cases from an hyper-endemic region in Costa Rica, were compared by phylogenetic analyses within the VP1 region. The outbreaks in all 531 cases, in 1992 and 1999, respectively, were presumed water borne. In the first outbreak, HAV RNA could be detected in 70% of the cases sampled during 6 weeks after onset of jaundice. In the hyper… CONTINUE READING

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