Pressure-volume curves in smokers. Comparison with alpha-1-antitrypsin deficiency.

  title={Pressure-volume curves in smokers. Comparison with alpha-1-antitrypsin deficiency.},
  author={David H. Eidelman and Heberto Ghezzo and Won Duk Kim and Robert Hyatt and Manuel G. Cosio},
  journal={The American review of respiratory disease},
  volume={139 6},
The diagnosis of emphysema has been associated with changes in the appearance of the pressure-volume (P-V) curve: reduced maximal recoil pressure, increased lung volume, and a shift in the position of the curve to the left. In our clinical practice, we have observed that patients with chronic obstructive lung disease (COPD) commonly had P-V curves with reduced maximal elastic recoil that are difficult to classify according to the classic description of the P-V curve in emphysema. In order to… CONTINUE READING


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