Pressure-derived fractional flow reserve to assess serial epicardial stenoses: theoretical basis and animal validation.

@article{Bruyne2000PressurederivedFF,
  title={Pressure-derived fractional flow reserve to assess serial epicardial stenoses: theoretical basis and animal validation.},
  author={Bernard de Bruyne and Nico H. J. Pijls and Guy R. Heyndrickx and Dominique Hodeige and Richard L. Kirkeeide and Kenneth L. Gould},
  journal={Circulation},
  year={2000},
  volume={101 15},
  pages={
          1840-7
        }
}
Background-Fractional flow reserve (FFR) is an index of stenosis severity validated for isolated stenoses. This study develops the theoretical basis and experimentally validates equations for predicting FFR of sequential stenoses separately. Methods and Results-For 2 stenoses in series, equations were derived to predict FFR (FFR(pred)) of each stenosis separately (ie, as if the other one were removed) from arterial pressure (P(a)), pressure between the 2 stenoses (P(m)), distal coronary… CONTINUE READING

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