• Corpus ID: 245704435

Pressure -- area loop based phenotypic classification and mechanics of esophagogastric junction physiology

@inproceedings{Elisha2022PressureA,
  title={Pressure -- area loop based phenotypic classification and mechanics of esophagogastric junction physiology},
  author={Guy Elisha and Sourav Halder and Shashank Acharya and Dustin A. Carlson and Wenjun Kou and Peter J. Kahrilas and John E. Pandolfino and Neelesh A. Patankar},
  year={2022}
}
The esophagogastric junction (EGJ) is located at the distal end of the esophagus and acts as a valve allowing swallowed materials to enter the stomach and preventing acid reflux. Irregular weakening or stiffening of the EGJ muscles result in changes to its opening and closing patterns which can progress into esophageal disorders. Therefore, understanding the physics behind the opening and closing cycle of the EGJ provides a mechanistic insight into its function and can help identify the… 

A mechanics--based perspective on the function of human sphincters during functional luminal imaging probe manometry

TLDR
This work provides a fundamental mechanical understanding of human sphincters and can be used to identify normal and abnormal phenotypes for the different spharkers and help in creating physiomarkers based on work calculation.

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