Pressor sensitivities to vasopressin, angiotensin II, or methoxamine in diabetic rats.

@article{Hebden1987PressorST,
  title={Pressor sensitivities to vasopressin, angiotensin II, or methoxamine in diabetic rats.},
  author={R A Hebden and Terence Bennett and Sheila M. Gardiner},
  journal={The American journal of physiology},
  year={1987},
  volume={253 5 Pt 2},
  pages={
          R726-34
        }
}
We investigated the pressor sensitivities to vasopressin, angiotensin II, and methoxamine of intact and ganglion-blocked rats that had been treated 21 days earlier with streptozotocin or saline. No differences in blood pressure or heart rate responses to vasopressin or angiotensin II were found between the intact groups when these peptides were administered intravenously in equimolar doses. After ganglion blockade a significant enhancement in pressor responsiveness to both vasopressin and… CONTINUE READING

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