Pressor responsiveness in corticosteroid-induced hypertension in humans.

  title={Pressor responsiveness in corticosteroid-induced hypertension in humans.},
  author={Marinis Pirpiris and Krishnankutty Sudhir and S T Yeung and Garry L Jennings and Judith Ann Whitworth},
  volume={19 6 Pt 1},
In previous studies short-term cortisol increased cold pressor responses and the rise in forearm vascular resistance accompanying intra-arterial norepinephrine without an increase in overall resting sympathetic nervous activity. The present study examined whether these alterations in pressor response are glucocorticoid or mineralocorticoid effects, or both. Normal male subjects (n = 12) received either fludrocortisone, 0.3 mg daily (n = 6), or dexamethasone, 3 mg daily (n = 6), for 7 days… CONTINUE READING