Preserved vasopressin response to osmostimulation despite decreased basal vasopressin levels in long-term abstinent alcoholics.


BACKGROUND Basal arginine vasopressin (AVP) plasma levels in alcoholic patients are persistently decreased over months of controlled alcohol abstinence. As a potential explanation of this phenomenon, a reduction of AVP immunoreactive neurons was described in the hypothalamus of alcohol-dependent humans and rodents. This study was therefore designed to… (More)


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