Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: radiation dose dependency and compensatory mechanisms.

Abstract

PURPOSE To study the ability of a prophylactic pilocarpine administration to preserve the rat parotid gland function after unilateral irradiation with graded doses of X-rays. METHODS The right parotid gland of male albino Wistar rats was irradiated with single doses of X-rays (10-30 Gy, at 1.5 Gy min(-1)). Pilocarpine (4 mg/kg) was administered… (More)

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@article{Roesink1999PreservationOT, title={Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: radiation dose dependency and compensatory mechanisms.}, author={Judith M. Roesink and Antonius W. T. Konings and Chris H. J. Terhaard and J. J. Battermann and Harm H. Kampinga and Robert Paul Coppes}, journal={International journal of radiation oncology, biology, physics}, year={1999}, volume={45 2}, pages={483-9} }