Preservation of splenic function by autotransplantation of traumatized spleen in man.

@article{Patel1981PreservationOS,
  title={Preservation of splenic function by autotransplantation of traumatized spleen in man.},
  author={Jawaharlal M. Patel and James Scott Williams and B Shmigel and J R Hinshaw},
  journal={Surgery},
  year={1981},
  volume={90 4},
  pages={683-8}
}
Splenectomy is known to increase the risk of overwhelming bacterial infection. Characteristically, there is a decrease in immunoglobulin IgM, properdin, and T-lymphocytes; impaired primary antibody response to antigen challenge; an altered opsonic function; and a tuftsin deficiency. Because the spleen is important in host defense, preservation of traumatized splenic tissue has been advocated. Splenic autotransplantation has been suggested as a method of preserving function, and this concept is… CONTINUE READING