Preservation of monocyte effector functions against Mycobacterium avium-M. intracellulare in patients with AIDS.

@article{Johnson1991PreservationOM,
  title={Preservation of monocyte effector functions against Mycobacterium avium-M. intracellulare in patients with AIDS.},
  author={John Johnson and Hiroe Shiratsuchi and Hirokazu Toba and Jerrold J. Ellner},
  journal={Infection and immunity},
  year={1991},
  volume={59 10},
  pages={3639-45}
}
Mycobacterium avium-M. intracellulare is a frequent cause of late disseminated infection in patients with AIDS. The ability of human peripheral blood monocytes to phagocytose and kill M. avium was examined in an in vitro model. Monocytes were obtained from 13 healthy volunteers and 11 patients with AIDS, three of whom had documented disseminated M. avium infection. Monocytes were precultured for 2 days before infection with two AIDS-associated and two non-AIDS-associated strains of M. avium… CONTINUE READING

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