Preservation of limbic and paralimbic structures in aging.

  title={Preservation of limbic and paralimbic structures in aging.},
  author={Stuart M. Grieve and C. Richard Clark and Leanne M. Williams and Anthony J. Peduto and Evian Gordon},
  journal={Human brain mapping},
  volume={25 4},
Patterns of gray matter (GM) loss were measured in 223 healthy subjects spanning eight decades. We observed significant clusters of accelerated loss in focal regions of the frontal and parietal cortices, including the dorsolateral frontal cortex, pre- and postcentral gyrus, and the inferior and superior parietal lobes. The rate of loss in these clusters was approximately twice that of the global average. By contrast, clusters of significant GM preservation were found in limbic and paralimbic… CONTINUE READING
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