Preservation of bone morphogenetic protein in heat-treated bone.


In operations of bone tumors, reimplantation of resected bone after boiling or autoclaving is a simple means of obtaining both tumor necrosis and skeletal reconstruction. However, such reimplants lose their osteogenesity. We investigated whether bone inductive ability could be maintained in heat-treated bone. Bone morphogenetic protein (BMP) extracted from… (More)


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@article{Nakanishi1992PreservationOB, title={Preservation of bone morphogenetic protein in heat-treated bone.}, author={Kuniaki Nakanishi and Kiyoshi Sato and Toshiyuki Sato and Megumi Takahashi and Nobuyuki Fukaya and Tetsuji Miura}, journal={Nihon Seikeigeka Gakkai zasshi}, year={1992}, volume={66 9}, pages={949-55} }