Preservation of amino acids during long term ischemia and subsequent reflow with supplementation of L-arginine, the nitric oxide precursor, in the rat heart

@article{Desrois2003PreservationOA,
  title={Preservation of amino acids during long term ischemia and subsequent reflow with supplementation of L-arginine, the nitric oxide precursor, in the rat heart},
  author={Martine Desrois and M. Sciaky and Carole Lan and Patrick J. Cozzone and Monique Bernard},
  journal={Amino Acids},
  year={2003},
  volume={24},
  pages={141-148}
}
 We investigated whether L-arginine, used in heart preservation to limit endothelial damage, may influence the pool of amino acids during long term ischemia and reflow. Isolated isovolumic rat hearts (n = 23) were submitted to 8 h of hypothermic ischemia after cardioplegic arrest with the Centre de Résonance Magnétique Biologique et Médicale (CRMBM… CONTINUE READING