Presentation of human minor histocompatibility antigens by HLA-B35 and HLA-B38 molecules.

@article{Yamamoto1990PresentationOH,
  title={Presentation of human minor histocompatibility antigens by HLA-B35 and HLA-B38 molecules.},
  author={J Jeremy Yamamoto and A I Kariyone and Nobuo Akiyama and Kyoichi Kano and Masafumi Takiguchi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 7},
  pages={2583-7}
}
Cytotoxic T lymphocyte (CTL) clones specific for human minor histocompatibility antigens (hmHAs) were produced from a patient who had been grafted with the kidneys from his mother and two HLA-identical sisters. Of eight CTL clones generated, four recognized an hmHA (hmHA-1) expressed on cells from the mother and sister 3 (second donor); two recognized another antigen (hmHA-2) on cells from the father, sister 2 (third donor), and sister 3; and the remaining two clones recognized still another… CONTINUE READING