Presentation of donor major histocompatibility complex class II antigens by dna vaccination prolongs heart allograft survival.

Abstract

BACKGROUND Donor major histocompatibility complex (MHC) antigens play an important role in both allograft rejection and tolerance. With the use of several animal models, it has been shown that presentation of donor antigens before transplantation can lead to allograft tolerance. Vaccination of animals with a DNA plasmid encoding an antigen enables highly… (More)

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@article{Pche2004PresentationOD, title={Presentation of donor major histocompatibility complex class II antigens by dna vaccination prolongs heart allograft survival.}, author={H{\'e}l{\`e}ne P{\^e}che and Bryce J. W. van Denderen and Jean Christian Roussel and Benjamin Trinit{\'e} and Jean Paul Soulillou and Maria Cristina Cuturi}, journal={Transplantation}, year={2004}, volume={77 5}, pages={733-40} }